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PD-L1 regulates cell proliferation and apoptosis in acute myeloid leukemia by activating PI3K-AKT signaling pathway

As immune checkpoint inhibitors (ICIs) continue to advance, more evidence has emerged that anti-PD-1/PD-L1 immunotherapy is an effective treatment against cancers. Known as the programmed death ligand-1 (PD-L1), this co-inhibitory ligand contributes to T cell exhaustion by interacting with programme...

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Detalles Bibliográficos
Autores principales: Wang, Fang, Yang, Liqiong, Xiao, Mintao, Zhang, Zhuo, Shen, Jing, Anuchapreeda, Songyot, Tima, Singkome, Chiampanichayakul, Sawitree, Xiao, Zhangang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259561/
https://www.ncbi.nlm.nih.gov/pubmed/35794161
http://dx.doi.org/10.1038/s41598-022-15020-0