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Genome-wide linkage analysis combined with genome sequencing in large families with intracranial aneurysms
Rupture of an intracranial aneurysm (IA) leads to aneurysmal subarachnoid haemorrhage (ASAH), a severe type of stroke. Some rare variants that cause IA in families have been identified, but still, the majority of genetic causes, as well as the biological mechanisms of IA development and rupture, rem...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259640/ https://www.ncbi.nlm.nih.gov/pubmed/35228681 http://dx.doi.org/10.1038/s41431-022-01059-0 |