Application of multiplex amplicon deep-sequencing (MAD-seq) to screen for putative drug resistance markers in the Necator americanus isotype-1 β-tubulin gene

Global control of hookworm infections relies on periodic Mass Drug Administration of benzimidazole drugs to high-risk groups, regardless of infection status. Mutations in the isotype-1 β-tubulin gene have been identified in veterinary nematodes, resulting in structural changes and reduced drug-bindi...

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Detalles Bibliográficos
Autores principales: George, Santosh, Suwondo, Peter, Akorli, Jewelna, Otchere, Joseph, Harrison, Lisa M., Bilguvar, Kaya, Knight, James R., Humphries, Debbie, Wilson, Michael D., Caccone, Adalgisa, Cappello, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259660/
https://www.ncbi.nlm.nih.gov/pubmed/35794459
http://dx.doi.org/10.1038/s41598-022-15718-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259660/
https://www.ncbi.nlm.nih.gov/pubmed/35794459
http://dx.doi.org/10.1038/s41598-022-15718-1

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