p63 silencing induces epigenetic modulation to enhance human cardiac fibroblast to cardiomyocyte-like differentiation

Direct cell reprogramming represents a promising new myocardial regeneration strategy involving in situ transdifferentiation of cardiac fibroblasts into induced cardiomyocytes. Adult human cells are relatively resistant to reprogramming, however, likely because of epigenetic restraints on reprogramm...

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Detalles Bibliográficos
Autores principales: Pinnamaneni, Jaya Pratap, Singh, Vivek P., Kim, Mary B., Ryan, Christopher T., Pugazenthi, Aarthi, Sanagasetti, Deepthi, Mathison, Megumi, Yang, Jianchang, Rosengart, Todd K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259667/
https://www.ncbi.nlm.nih.gov/pubmed/35794145
http://dx.doi.org/10.1038/s41598-022-15559-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259667/
https://www.ncbi.nlm.nih.gov/pubmed/35794145
http://dx.doi.org/10.1038/s41598-022-15559-y

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