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People with HIV have higher percentages of circulating CCR5+ CD8+ T cells and lower percentages of CCR5+ regulatory T cells

CCR5 is the main HIV co-receptor. We aimed to (1) compare CCR5 expression on immune cells between people living with HIV (PLHIV) using combination antiretroviral therapy (cART) and HIV-uninfected controls, (2) relate CCR5 expression to viral reservoir size and (3) assess determinants of CCR5 express...

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Detalles Bibliográficos
Autores principales: van Eekeren, Louise E., Matzaraki, Vasiliki, Zhang, Zhenhua, van de Wijer, Lisa, Blaauw, Marc J. T., de Jonge, Marien I., Vandekerckhove, Linos, Trypsteen, Wim, Joosten, Leo A. B., Netea, Mihai G., de Mast, Quirijn, Koenen, Hans J. P. M., Li, Yang, van der Ven, André J. A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259737/
https://www.ncbi.nlm.nih.gov/pubmed/35794176
http://dx.doi.org/10.1038/s41598-022-15646-0