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Palmatine Protects Against MSU-Induced Gouty Arthritis via Regulating the NF-κB/NLRP3 and Nrf2 Pathways

PURPOSE: Gouty arthritis could be triggered by the deposition of monosodium uric acid (MSU) crystals. Palmatine (PAL), a protoberberine alkaloid, has been proven to possess compelling health-beneficial activities. In this study, we aimed to explore the effect of PAL on LPS plus MSU crystal-stimulate...

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Detalles Bibliográficos
Autores principales: Cheng, Juan-Juan, Ma, Xing-Dong, Ai, Gao-Xiang, Yu, Qiu-Xia, Chen, Xiao-Ying, Yan, Fang, Li, Yu-Cui, Xie, Jian-Hui, Su, Zi-Ren, Xie, Qing-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259749/
https://www.ncbi.nlm.nih.gov/pubmed/35812134
http://dx.doi.org/10.2147/DDDT.S356307