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Heparan sulfate proteoglycans mediate prion-like α-synuclein toxicity in Parkinson’s in vivo models
Parkinson’s disease (PD) is a debilitating neurodegenerative disorder characterized by progressive motor decline and the aggregation of α-synuclein protein. Growing evidence suggests that α-synuclein aggregates may spread from neurons of the digestive tract to the central nervous system in a prion-l...
Autores principales: | Chen, Merry, Vincent, Julie, Ezeanii, Alexis, Wakade, Saurabh, Yerigenahally, Shobha, Mor, Danielle E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259873/ https://www.ncbi.nlm.nih.gov/pubmed/35790300 http://dx.doi.org/10.26508/lsa.202201366 |
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