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Biophysical Screening Pipeline for Cryo-EM Grid Preparation of Membrane Proteins

Successful sample preparation is the foundation to any structural biology technique. Membrane proteins are of particular interest as these are important targets for drug design, but also notoriously difficult to work with. For electron cryo-microscopy (cryo-EM), the biophysical characterization of s...

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Detalles Bibliográficos
Autores principales: Niebling, Stephan, Veith, Katharina, Vollmer, Benjamin, Lizarrondo, Javier, Burastero, Osvaldo, Schiller, Janina, Struve García, Angelica, Lewe, Philipp, Seuring, Carolin, Witt, Susanne, García-Alai, María
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9259969/
https://www.ncbi.nlm.nih.gov/pubmed/35813810
http://dx.doi.org/10.3389/fmolb.2022.882288