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Design, Synthesis, and Evaluation of Anticonvulsant Activities of New Triazolopyrimidine Derivatives

Epilepsy, a severe brain disease affecting a large population, is treated mainly by antiepileptic drugs (AEDs). However, toxicity, intolerance, and low efficiency of the available AEDs have prompted the continual attempts in the discovery of new AEDs. In this study, we discovered a skeleton of triaz...

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Detalles Bibliográficos
Autores principales: Song, Mingxia, Zhao, Wennan, Zhu, Yangnv, Liu, Wenli, Deng, Xianqing, Huang, Yushan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260081/
https://www.ncbi.nlm.nih.gov/pubmed/35815216
http://dx.doi.org/10.3389/fchem.2022.925281