Gentiopicroside Ameliorates Diabetic Renal Tubulointerstitial Fibrosis via Inhibiting the AT1R/CK2/NF-κB Pathway

Renal tubulointerstitial fibrosis (TIF), characterized by epithelial-to-mesenchymal transition (EMT) of renal tubular epithelial cells, is the typical pathological alteration in diabetic nephropathy. Gentiopicroside (GPS), a natural compound with anti-inflammatory activity, has been demonstrated to...

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Detalles Bibliográficos
Autores principales: Xu, Zhanchi, Zhang, Meng, Wang, Yu, Chen, Rui, Xu, Shiyue, Sun, Xiaohong, Yang, Yan, Lin, Zeyuan, Wang, Shaogui, Huang, Heqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260113/
https://www.ncbi.nlm.nih.gov/pubmed/35814242
http://dx.doi.org/10.3389/fphar.2022.848915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260113/
https://www.ncbi.nlm.nih.gov/pubmed/35814242
http://dx.doi.org/10.3389/fphar.2022.848915

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