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The Effect of Triptolide Combined With Crocin on Arthritis in Mice: From Side Effect Attenuation to Therapy

Clinical use of triptolide (TP) is restricted due to severe toxicity. This study assessed the protective effect of crocin (CR) as a natural antioxidant against TP-induced toxicity in bovine collagen type II-induced arthritis (CIA) in mice. The mice in the CIA model group showed macroscopic signs of...

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Detalles Bibliográficos
Autores principales: Yan, Min, Yan, Yinyin, Zhang, Zhenqiang, Wang, Guoqiang, Shi, Wenbo, Jiang, Mengyuan, Zhao, Junwei, Wu, Xiangxiang, Zeng, Huahui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260116/
https://www.ncbi.nlm.nih.gov/pubmed/35814255
http://dx.doi.org/10.3389/fphar.2022.908227