Single-cell RNA sequencing reveals that BMPR2 mutation regulates right ventricular function via ID genes

BACKGROUND: Mutations in bone morphogenetic protein type II receptor (BMPR2) have been found in patients with congenital heart disease-associated pulmonary arterial hypertension (CHD-PAH). Our study aimed to clarify whether deficient BMPR2 signalling acts through downstream effectors, inhibitors of...

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Detalles Bibliográficos
Autores principales: Du, Mingxia, Jiang, Haibin, Liu, Hongxian, Zhao, Xin, Zhou, Yu, Zhou, Fang, Piao, Chunmei, Xu, Guoqiang, Ma, Feng, Wang, Jianan, Perros, Frederic, Morrell, Nicholas W., Gu, Hong, Yang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260124/
https://www.ncbi.nlm.nih.gov/pubmed/34857612
http://dx.doi.org/10.1183/13993003.00327-2021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260124/
https://www.ncbi.nlm.nih.gov/pubmed/34857612
http://dx.doi.org/10.1183/13993003.00327-2021

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