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Lysyl oxidase like 2 is increased in asthma and contributes to asthmatic airway remodelling

BACKGROUND: Airway smooth muscle (ASM) cells are fundamental to asthma pathogenesis, influencing bronchoconstriction, airway hyperresponsiveness and airway remodelling. The extracellular matrix (ECM) can influence tissue remodelling pathways; however, to date no study has investigated the effect of...

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Detalles Bibliográficos
Autores principales: Ramis, Jopeth, Middlewick, Robert, Pappalardo, Francesco, Cairns, Jennifer T., Stewart, Iain D., John, Alison E., Naveed, Shams-Un-Nisa, Krishnan, Ramaswamy, Miller, Suzanne, Shaw, Dominick E., Brightling, Christopher E., Buttery, Lee, Rose, Felicity, Jenkins, Gisli, Johnson, Simon R., Tatler, Amanda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260127/
https://www.ncbi.nlm.nih.gov/pubmed/34996828
http://dx.doi.org/10.1183/13993003.04361-2020