Pyruvate Dehydrogenase Kinase Protects Dopaminergic Neurons from Oxidative Stress in Drosophila DJ-1 Null Mutants

DJ-1 is one of the causative genes of early-onset familial Parkinson’s disease (PD). As a result, DJ-1 influences the pathogenesis of sporadic PD. DJ-1 has various physiological functions that converge to control the levels of intracellular reactive oxygen species (ROS). Based on genetic analyses th...

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Detalles Bibliográficos
Autores principales: Lee, Yoonjeong, Kim, Jaehyeon, Kim, Hyunjin, Han, Ji Eun, Kim, Sohee, Kang, Kyong-hwa, Kim, Donghoon, Kim, Jong-Min, Koh, Hyongjong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260132/
https://www.ncbi.nlm.nih.gov/pubmed/35444068
http://dx.doi.org/10.14348/molcells.2022.5002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260132/
https://www.ncbi.nlm.nih.gov/pubmed/35444068
http://dx.doi.org/10.14348/molcells.2022.5002

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