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Pyruvate Dehydrogenase Kinase Protects Dopaminergic Neurons from Oxidative Stress in Drosophila DJ-1 Null Mutants
DJ-1 is one of the causative genes of early-onset familial Parkinson’s disease (PD). As a result, DJ-1 influences the pathogenesis of sporadic PD. DJ-1 has various physiological functions that converge to control the levels of intracellular reactive oxygen species (ROS). Based on genetic analyses th...
Autores principales: | Lee, Yoonjeong, Kim, Jaehyeon, Kim, Hyunjin, Han, Ji Eun, Kim, Sohee, Kang, Kyong-hwa, Kim, Donghoon, Kim, Jong-Min, Koh, Hyongjong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society for Molecular and Cellular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260132/ https://www.ncbi.nlm.nih.gov/pubmed/35444068 http://dx.doi.org/10.14348/molcells.2022.5002 |
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