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Improving the Safety of Mesenchymal Stem Cell-Based Ex Vivo Therapy Using Herpes Simplex Virus Thymidine Kinase

Human mesenchymal stem cells (MSCs) are multipotent stem cells that have been intensively studied as therapeutic tools for a variety of disorders. To enhance the efficacy of MSCs, therapeutic genes are introduced using retroviral and lentiviral vectors. However, serious adverse events (SAEs) such as...

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Detalles Bibliográficos
Autores principales: Bashyal, Narayan, Lee, Tae-Young, Chang, Da-Young, Jung, Jin-Hwa, Kim, Min Gyeong, Acharya, Rakshya, Kim, Sung-Soo, Oh, Il-Hoan, Suh-Kim, Haeyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260133/
https://www.ncbi.nlm.nih.gov/pubmed/35356894
http://dx.doi.org/10.14348/molcells.2022.5015