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Targeting the Leukemic stem cell protein machinery by inhibition of mitochondrial pyrimidine synthesis
Acute Myeloid Leukemia is one of the most aggressive blood cancers with a high frequency of relapse. While standard chemotherapy is able to target rapidly proliferating immature blasts, it fails to eradicate slowly proliferating Leukemic Stem Cells. Therefore, new therapeutic strategies that efficie...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260207/ https://www.ncbi.nlm.nih.gov/pubmed/35694783 http://dx.doi.org/10.15252/emmm.202216171 |