Sigma‐1 receptor attenuates osteoclastogenesis by promoting ER‐associated degradation of SERCA2

Sigma‐1 receptor (Sigmar1) is a specific chaperone located in the mitochondria‐associated endoplasmic reticulum membrane (MAM) and plays a role in several physiological processes. However, the role of Sigmar1 in bone homeostasis remains unknown. Here, we show that mice lacking Sigmar1 exhibited seve...

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Detalles Bibliográficos
Autores principales: Wei, Xiaoan, Zheng, Zeyu, Feng, Zhenhua, Zheng, Lin, Tao, Siyue, Zheng, Bingjie, Huang, Bao, Zhang, Xuyang, Liu, Junhui, Chen, Yilei, Zong, Wentian, Shan, Zhi, Fan, Shunwu, Chen, Jian, Zhao, Fengdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260208/
https://www.ncbi.nlm.nih.gov/pubmed/35611810
http://dx.doi.org/10.15252/emmm.202115373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260208/
https://www.ncbi.nlm.nih.gov/pubmed/35611810
http://dx.doi.org/10.15252/emmm.202115373

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