Mitochondrial HSF1 triggers mitochondrial dysfunction and neurodegeneration in Huntington's disease

Aberrant localization of proteins to mitochondria disturbs mitochondrial function and contributes to the pathogenesis of Huntington’s disease (HD). However, the crucial factors and the molecular mechanisms remain elusive. Here, we found that heat shock transcription factor 1 (HSF1) accumulates in th...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chunyue, Fu, Zixing, Wu, Shanshan, Wang, Xiaosong, Zhang, Shengrong, Chu, Chu, Hong, Yuan, Wu, Wenbo, Chen, Shengqi, Jiang, Yueqing, Wu, Yang, Song, Yongbo, Liu, Yan, Guo, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260212/
https://www.ncbi.nlm.nih.gov/pubmed/35670111
http://dx.doi.org/10.15252/emmm.202215851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260212/
https://www.ncbi.nlm.nih.gov/pubmed/35670111
http://dx.doi.org/10.15252/emmm.202215851

Ejemplares similares