Identification of Small-Molecule Inhibitors for Osteosarcoma Targeted Therapy: Synchronizing In Silico, In Vitro, and In Vivo Analyses

Objective: The study aimed to explore a new approach for the treatment of osteosarcoma through combining biomaterials with next-generation small molecule–based targeted therapy. Methods: The model of osteosarcoma was established by 4-hydroxyaminoquinoline 1-oxide (4-HAQO) in mice while the collagen-...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Juan, Yao, Qi, Peng, Yu, Dong, Zhihong, Tang, Lu, Su, Xiaoyu, Liu, Lishuang, Chen, Cheng, Ramalingam, Murugan, Cheng, Lijia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260275/
https://www.ncbi.nlm.nih.gov/pubmed/35814015
http://dx.doi.org/10.3389/fbioe.2022.921107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260275/
https://www.ncbi.nlm.nih.gov/pubmed/35814015
http://dx.doi.org/10.3389/fbioe.2022.921107

Ejemplares similares