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Identification of Small-Molecule Inhibitors for Osteosarcoma Targeted Therapy: Synchronizing In Silico, In Vitro, and In Vivo Analyses

Objective: The study aimed to explore a new approach for the treatment of osteosarcoma through combining biomaterials with next-generation small molecule–based targeted therapy. Methods: The model of osteosarcoma was established by 4-hydroxyaminoquinoline 1-oxide (4-HAQO) in mice while the collagen-...

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Detalles Bibliográficos
Autores principales:	Liu, Juan, Yao, Qi, Peng, Yu, Dong, Zhihong, Tang, Lu, Su, Xiaoyu, Liu, Lishuang, Chen, Cheng, Ramalingam, Murugan, Cheng, Lijia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Bioengineering and Biotechnology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260275/ https://www.ncbi.nlm.nih.gov/pubmed/35814015 http://dx.doi.org/10.3389/fbioe.2022.921107

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