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A Common Human Brain-Derived Neurotrophic Factor Polymorphism Leads to Prolonged Depression of Excitatory Synaptic Transmission by Isoflurane in Hippocampal Cultures

Multiple presynaptic and postsynaptic targets have been identified for the reversible neurophysiological effects of general anesthetics on synaptic transmission and neuronal excitability. However, the synaptic mechanisms involved in persistent depression of synaptic transmission resulting in more pr...

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Detalles Bibliográficos
Autores principales: Williams, Riley A., Johnson, Kenneth W., Lee, Francis S., Hemmings, Hugh C., Platholi, Jimcy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260310/
https://www.ncbi.nlm.nih.gov/pubmed/35813074
http://dx.doi.org/10.3389/fnmol.2022.927149