Cargando…

Extracting physical characteristics of higher-order chromatin structures from 3D image data

Higher-order chromatin structures have functional impacts on gene regulation and cell identity determination. Using high-throughput sequencing (HTS)-based methods like Hi-C, active or inactive compartments and open or closed topologically associating domain (TAD) structures can be identified on a ce...

Descripción completa

Detalles Bibliográficos
Autores principales: Lamberti, William Franz, Zang, Chongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260447/
https://www.ncbi.nlm.nih.gov/pubmed/35832633
http://dx.doi.org/10.1016/j.csbj.2022.06.018