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Inhibiting uptake of extracellular vesicles derived from senescent bone marrow mesenchymal stem cells by muscle satellite cells attenuates sarcopenia

OBJECTIVE: Osteoporosis is associated with senescence of bone marrow mesenchymal stem cells (BMSCs). Extracellular vesicles derived from senescent BMSCs (BMSC-EVs) could be uptaken by muscle satellite cells (SCs). We hypothesized that inhibiting the uptake of harmful BMSC-EVs by SCs could prevent pa...

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Detalles Bibliográficos
Autores principales: Dai, Hanhao, Zheng, Wu, Luo, Jun, Yu, Guoyu, Song, Chao, Wu, Yijing, Xu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260455/
https://www.ncbi.nlm.nih.gov/pubmed/35846725
http://dx.doi.org/10.1016/j.jot.2022.06.002