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Identification of Highly Cross-Reactive Mimotopes for a Public T Cell Response in Murine Melanoma

While immune checkpoint blockade results in durable responses for some patients, many others have not experienced such benefits. These treatments rely upon reinvigorating specific T cell-antigen interactions. However, it is often unknown what antigens are being recognized by T cells or how to potent...

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Detalles Bibliográficos
Autores principales: Grace, Beth E., Backlund, Coralie M., Morgan, Duncan M., Kang, Byong H., Singh, Nishant K., Huisman, Brooke D., Rappazzo, C. Garrett, Moynihan, Kelly D., Maiorino, Laura, Dobson, Connor S., Kyung, Taeyoon, Gordon, Khloe S., Holec, Patrick V., Mbah, Overbeck C. Takou, Garafola, Daniel, Wu, Shengwei, Love, J. Christopher, Wittrup, K. Dane, Irvine, Darrell J., Birnbaum, Michael E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260506/
https://www.ncbi.nlm.nih.gov/pubmed/35812387
http://dx.doi.org/10.3389/fimmu.2022.886683