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Genome-Wide Association Study and Gene-Based Analysis of Participants With Hemophilia A and Inhibitors in the My Life, Our Future Research Repository

INTRODUCTION: Up to 30% of individuals with hemophilia A develop inhibitors to replacement factor VIII (FVIII), rendering the treatment ineffective. The underlying mechanism of inhibitor development remains poorly understood. The My Life, Our Future Research Repository (MLOF RR) has gathered F8 and...

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Detalles Bibliográficos
Autores principales: Lessard, Samuel, He, Chunla, Rajpal, Deepak K., Klinger, Katherine, Loh, Christine, Harris, Tim, Dumont, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260508/
https://www.ncbi.nlm.nih.gov/pubmed/35814780
http://dx.doi.org/10.3389/fmed.2022.903838