Peptidome Surveillance Across Evolving SARS-CoV-2 Lineages Reveals HLA Binding Conservation in Nucleocapsid Among Variants With Most Potential for T-Cell Epitope Loss in Spike

To provide a unique global view of the relative potential for evasion of CD8+ and CD4+ T cells by SARS-CoV-2 lineages as they evolve over time, we performed a comprehensive analysis of predicted HLA-I and HLA-II binding peptides in Spike (S) and Nucleocapsid (N) protein sequences of all available SA...

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Detalles Bibliográficos
Autores principales: Wnuk, Kamil, Sudol, Jeremi, Spilman, Patricia, Soon-Shiong, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260595/
https://www.ncbi.nlm.nih.gov/pubmed/35812370
http://dx.doi.org/10.3389/fimmu.2022.918928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260595/
https://www.ncbi.nlm.nih.gov/pubmed/35812370
http://dx.doi.org/10.3389/fimmu.2022.918928

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