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Thioredoxin Reductase Inhibitors as Potential Antitumors: Mercury Compounds Efficacy in Glioma Cells

Glioblastoma multiforme (GBM) is the most aggressive and common form of glioma. GBM, like many other tumors, expresses high levels of redox proteins, such as thioredoxin (Trx) and thioredoxin reductase (TrxR), allowing tumor cells to cope with high levels of reactive oxygen species (ROS) and resist...

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Detalles Bibliográficos
Autores principales: Pires, Vanessa, Bramatti, Isabella, Aschner, Michael, Branco, Vasco, Carvalho, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260667/
https://www.ncbi.nlm.nih.gov/pubmed/35813817
http://dx.doi.org/10.3389/fmolb.2022.889971