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Optimizing Antimicrobial Therapy by Integrating Multi-Omics With Pharmacokinetic/Pharmacodynamic Models and Precision Dosing

In the era of “Bad Bugs, No Drugs,” optimizing antibiotic therapy against multi-drug resistant (MDR) pathogens is crucial. Mathematical modelling has been employed to further optimize dosing regimens. These models include mechanism-based PK/PD models, systems-based models, quantitative systems pharm...

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Detalles Bibliográficos
Autores principales: Yow, Hui-Yin, Govindaraju, Kayatri, Lim, Audrey Huili, Abdul Rahim, Nusaibah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260690/
https://www.ncbi.nlm.nih.gov/pubmed/35814236
http://dx.doi.org/10.3389/fphar.2022.915355