Spatial meta-transcriptomics reveal associations of intratumor bacteria burden with lung cancer cells showing a distinct oncogenic signature

BACKGROUND: The lung intratumor microbiome influences lung cancer tumorigenesis and treatment responses, but detailed data on the extent, location, and effects of microbes within lung tumors are missing, information needed for improved prognosis and treatment. METHODS: To address this gap, we develo...

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Detalles Bibliográficos
Autores principales: Wong-Rolle, Abigail, Dong, Qiang, Zhu, Yunhua, Divakar, Prajan, Hor, Jyh Liang, Kedei, Noemi, Wong, Madeline, Tillo, Desiree, Conner, Elizabeth A, Rajan, Arun, Schrump, David S, Jin, Chengcheng, Germain, Ronald N, Zhao, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Immunotherapy Biomarkers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260850/
https://www.ncbi.nlm.nih.gov/pubmed/35793869
http://dx.doi.org/10.1136/jitc-2022-004698

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260850/
https://www.ncbi.nlm.nih.gov/pubmed/35793869
http://dx.doi.org/10.1136/jitc-2022-004698

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