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Spatial meta-transcriptomics reveal associations of intratumor bacteria burden with lung cancer cells showing a distinct oncogenic signature
BACKGROUND: The lung intratumor microbiome influences lung cancer tumorigenesis and treatment responses, but detailed data on the extent, location, and effects of microbes within lung tumors are missing, information needed for improved prognosis and treatment. METHODS: To address this gap, we develo...
Autores principales: | Wong-Rolle, Abigail, Dong, Qiang, Zhu, Yunhua, Divakar, Prajan, Hor, Jyh Liang, Kedei, Noemi, Wong, Madeline, Tillo, Desiree, Conner, Elizabeth A, Rajan, Arun, Schrump, David S, Jin, Chengcheng, Germain, Ronald N, Zhao, Chen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260850/ https://www.ncbi.nlm.nih.gov/pubmed/35793869 http://dx.doi.org/10.1136/jitc-2022-004698 |
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