Cargando…

Downregulation of TNFR2 decreases survival gene expression, promotes apoptosis and affects the cell cycle of gastric cancer cells

BACKGROUND: Chronic inflammation due to Helicobacter pylori (H. pylori) infection promotes gastric carcinogenesis. Tumour necrosis factor-α (TNF-α), a key mediator of inflammation, induces cell survival or apoptosis by binding to two receptors (TNFR1 and TNFR2). TNFR1 can induce both survival and ap...

Descripción completa

Detalles Bibliográficos
Autores principales: Rossi, Ana Flávia Teixeira, da Silva Manoel-Caetano, Fernanda, Biselli, Joice Matos, Cabral, Ágata Silva, Saiki, Marilia de Freitas Calmon, Ribeiro, Marcelo Lima, Silva, Ana Elizabete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260869/
https://www.ncbi.nlm.nih.gov/pubmed/35979166
http://dx.doi.org/10.3748/wjg.v28.i24.2689