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Hyperoside ameliorates TNF-α-induced inflammation, ECM degradation and ER stress-mediated apoptosis via the SIRT1/NF-κB and Nrf2/ARE signaling pathways in vitro

Intervertebral disc degeneration (IDD) is the main pathogenesis of numerous cases of chronic neck and back pain, and has become the leading cause of spinal-related disability worldwide. Hyperoside is an active flavonoid glycoside that exhibits anti-inflammation, anti-oxidation and anti-apoptosis eff...

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Detalles Bibliográficos
Autores principales: Xie, Tian, Yuan, Jun, Mei, Ling, Li, Ping, Pan, Ruijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260875/
https://www.ncbi.nlm.nih.gov/pubmed/35730622
http://dx.doi.org/10.3892/mmr.2022.12776