Cargando…

Hyperoside ameliorates TNF-α-induced inflammation, ECM degradation and ER stress-mediated apoptosis via the SIRT1/NF-κB and Nrf2/ARE signaling pathways in vitro

Intervertebral disc degeneration (IDD) is the main pathogenesis of numerous cases of chronic neck and back pain, and has become the leading cause of spinal-related disability worldwide. Hyperoside is an active flavonoid glycoside that exhibits anti-inflammation, anti-oxidation and anti-apoptosis eff...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Tian, Yuan, Jun, Mei, Ling, Li, Ping, Pan, Ruijie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260875/ https://www.ncbi.nlm.nih.gov/pubmed/35730622 http://dx.doi.org/10.3892/mmr.2022.12776

Ejemplares similares

Hyperoside ameliorates periodontitis in rats by promoting osteogenic differentiation of BMSCs via activation of the NF‐κB pathway
por: Xu, Tao, et al.
Publicado: (2020)

Hyperoside Induces Breast Cancer Cells Apoptosis via ROS-Mediated NF-κB Signaling Pathway
por: Qiu, Jinxia, et al.
Publicado: (2019)

Relevance of SIRT1-NF-κB Axis as Therapeutic Target to Ameliorate Inflammation in Liver Disease
por: de Gregorio, Estefanía, et al.
Publicado: (2020)

ECM controls flow-induced NF-κB
por: Tuma, Rabiya S.
Publicado: (2005)

ECM signals ECM degradation
por: Powell, Kendall
Publicado: (2006)

Luteolin suppresses TNF-α-induced inflammatory injury and senescence of nucleus pulposus cells via the Sirt6/NF-κB pathway
por: Xie, Tian, et al.
Publicado: (2022)

Dietary Flavonoid Hyperoside Induces Apoptosis of Activated Human LX-2 Hepatic Stellate Cell by Suppressing Canonical NF-κB Signaling
por: Wang, Liwen, et al.
Publicado: (2016)

Down‐regulated in OA cartilage, SFMBT2 contributes to NF‐κB‐mediated ECM degradation
por: Hussain, Safdar, et al.
Publicado: (2018)

Hyperoside Ameliorates Renal Tubular Oxidative Damage and Calcium Oxalate Deposition in Rats through AMPK/Nrf2 Signaling Axis
por: Tian, Hongyang, et al.
Publicado: (2023)

Phillygenin inhibits inflammation in chondrocytes via the Nrf2/NF-κB axis and ameliorates osteoarthritis in mice
por: Zhang, Peng, et al.
Publicado: (2023)

Bergenin ameliorates airway inflammation and remodeling in asthma by activating SIRT1 in macrophages to regulate the NF-κB pathway
por: Huang, Dan, et al.
Publicado: (2022)

Bestrophin 3 Ameliorates TNFα-Induced Inflammation by Inhibiting NF-κB Activation in Endothelial Cells
por: Song, Wei, et al.
Publicado: (2014)

Hyperoside Ameliorates Diabetic Retinopathy via Anti-Oxidation, Inhibiting Cell Damage and Apoptosis Induced by High Glucose
por: Wu, Wei, et al.
Publicado: (2020)

The Clinical Significance of PR, ER, NF-κB, and TNF-α in Breast Cancer
por: Zhou, Xian-Long, et al.
Publicado: (2014)

Ameliorating Inflammation in Insulin-resistant Rat Adipose Tissue with Abdominal Massage Regulates SIRT1/NF-κB Signaling
por: Gao, Tianjiao, et al.
Publicado: (2022)

Hyperoside Attenuate Inflammation in HT22 Cells via Upregulating SIRT1 to Activities Wnt/β-Catenin and Sonic Hedgehog Pathways
por: Huang, Jin, et al.
Publicado: (2021)

Geraniol Ameliorates Doxorubicin-Mediated Kidney Injury through Alteration of Antioxidant Status, Inflammation, and Apoptosis: Potential Roles of NF-κB and Nrf2/Ho-1
por: AlAsmari, Abdullah F., et al.
Publicado: (2022)

Suppressing Syndecan-1 Shedding Ameliorates Intestinal Epithelial Inflammation through Inhibiting NF-κB Pathway and TNF-α
por: Zhang, Yan, et al.
Publicado: (2016)

Allisartan isoproxil attenuates oxidative stress and inflammation through the SIRT1/Nrf2/NF-κB signalling pathway in diabetic cardiomyopathy rats
por: Jin, Qinyang, et al.
Publicado: (2021)

Transcription factors Nrf2 and NF-κB contribute to inflammation and apoptosis induced by intestinal ischemia-reperfusion in mice
por: Meng, Qing-Tao, et al.
Publicado: (2017)

Naringenin ameliorates myocardial injury in STZ-induced diabetic mice by reducing oxidative stress, inflammation and apoptosis via regulating the Nrf2 and NF-κB signaling pathways
por: He, Yongpeng, et al.
Publicado: (2022)

Zoledronate promotes ECM degradation and apoptosis via Wnt/β-catenin
por: Xiao, Jialing, et al.
Publicado: (2022)

The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis: Nrf2/HMGB1 affects osteoarthritis
por: Li, Wenzhao, et al.
Publicado: (2023)

Aronia melanocarpa polysaccharide ameliorates inflammation and aging in mice by modulating the AMPK/SIRT1/NF-κB signaling pathway and gut microbiota
por: Zhao, Yingchun, et al.
Publicado: (2021)

Berberine suppresses apoptosis and extracellular matrix (ECM) degradation in nucleus pulposus cells and ameliorates disc degeneration in a rodent model
por: Chen, Yu, et al.
Publicado: (2018)

Mangiferin Prevents TBHP-Induced Apoptosis and ECM Degradation in Mouse Osteoarthritic Chondrocytes via Restoring Autophagy and Ameliorates Murine Osteoarthritis
por: Li, Yao, et al.
Publicado: (2019)

Corrigendum to “Suppressing Syndecan-1 Shedding Ameliorates Intestinal Epithelial Inflammation through Inhibiting NF-κB Pathway and TNF-α”
por: Zhang, Yan, et al.
Publicado: (2017)

Focal adhesions degrade the ECM
por: Short, Ben
Publicado: (2012)

Vicenin 3 ameliorates ECM degradation by regulating the MAPK pathway in SW1353 chondrocytes
por: Chen, Yue-Yuan, et al.
Publicado: (2021)

SIRT6 overexpression induces apoptosis of nasopharyngeal carcinoma by inhibiting NF-κB signaling
por: Ouyang, Lei, et al.
Publicado: (2018)

TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1
por: Etemadi, Nima, et al.
Publicado: (2015)

Curcumin Ameliorates Particulate Matter-Induced Pulmonary Injury through Bimodal Regulation of Macrophage Inflammation via NF-κB and Nrf2
por: Lee, Min Kook, et al.
Publicado: (2023)

Allyl isothiocyanate ameliorates lipid accumulation and inflammation in nonalcoholic fatty liver disease via the Sirt1/AMPK and NF-κB signaling pathways
por: Li, Chun-Xiao, et al.
Publicado: (2019)

Isovitexin Depresses Osteoarthritis Progression via the Nrf2/NF-κB Pathway: An in vitro Study
por: Hu, Xiaofen, et al.
Publicado: (2021)

Curcumenol Mitigates the Inflammation and Ameliorates the Catabolism Status of the Intervertebral Discs In Vivo and In Vitro via Inhibiting the TNFα/NFκB Pathway
por: Yang, Xiao, et al.
Publicado: (2022)

Correction: TRAF2 regulates TNF and NF-κB signalling to suppress apoptosis and skin inflammation independently of Sphingosine kinase 1
por: Etemadi, Nima, et al.
Publicado: (2017)

ceAF Ameliorates Diabetic Wound Healing by Alleviating Inflammation and Oxidative Stress via TLR4/NF-κB and Nrf2 Pathways
por: Li, Shiyan, et al.
Publicado: (2023)

TAZ ameliorates the microglia-mediated inflammatory response via the Nrf2-ROS-NF-κB pathway
por: Huang, Ji-Cheng, et al.
Publicado: (2022)

Hyperoside attenuates dextran sulfate sodium-induced colitis in mice possibly via activation of the Nrf2 signalling pathway
por: Yang, Lei, et al.
Publicado: (2017)

SIRT1 negatively regulates amyloid-beta-induced inflammation via the NF-κB pathway
por: Cao, L., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_m5t785qr9d1a8iifeu8sa10jno