Lactate receptor HCAR1 regulates cell growth, metastasis and maintenance of cancer-specific energy metabolism in breast cancer cells

Under aerobic conditions, the preferential use of anaerobic glycolysis by tumour cells leads to a high level of lactate accumulation in tumour microenvironment. Lactate acts not only as a cellular energy source but also as a signalling molecule that regulates cancer cell growth, metastasis and metab...

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Detalles Bibliográficos
Autores principales: Jin, Lili, Guo, Yanan, Chen, Jiawen, Wen, Zhenzhen, Jiang, Yibin, Qian, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260879/
https://www.ncbi.nlm.nih.gov/pubmed/35775372
http://dx.doi.org/10.3892/mmr.2022.12784

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260879/
https://www.ncbi.nlm.nih.gov/pubmed/35775372
http://dx.doi.org/10.3892/mmr.2022.12784

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