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Lactate receptor HCAR1 regulates cell growth, metastasis and maintenance of cancer-specific energy metabolism in breast cancer cells

Under aerobic conditions, the preferential use of anaerobic glycolysis by tumour cells leads to a high level of lactate accumulation in tumour microenvironment. Lactate acts not only as a cellular energy source but also as a signalling molecule that regulates cancer cell growth, metastasis and metab...

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Detalles Bibliográficos
Autores principales:	Jin, Lili, Guo, Yanan, Chen, Jiawen, Wen, Zhenzhen, Jiang, Yibin, Qian, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260879/ https://www.ncbi.nlm.nih.gov/pubmed/35775372 http://dx.doi.org/10.3892/mmr.2022.12784

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