A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins

[Image: see text] There is interest in the development of drugs to treat fungal infections due to the increasing threat of drug resistance, and here, we report the first crystallographic structure of the catalytic domain of a fungal squalene synthase (SQS), Aspergillus flavus SQS (AfSQS), a potentia...

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Detalles Bibliográficos
Autores principales: Malwal, Satish R., Shang, Na, Liu, Weidong, Li, Xian, Zhang, Lilan, Chen, Chun-Chi, Guo, Rey-Ting, Oldfield, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260892/
https://www.ncbi.nlm.nih.gov/pubmed/35811857
http://dx.doi.org/10.1021/acsomega.2c01924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260892/
https://www.ncbi.nlm.nih.gov/pubmed/35811857
http://dx.doi.org/10.1021/acsomega.2c01924

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