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A Structural and Bioinformatics Investigation of a Fungal Squalene Synthase and Comparisons with Other Membrane Proteins
[Image: see text] There is interest in the development of drugs to treat fungal infections due to the increasing threat of drug resistance, and here, we report the first crystallographic structure of the catalytic domain of a fungal squalene synthase (SQS), Aspergillus flavus SQS (AfSQS), a potentia...
Autores principales: | Malwal, Satish R., Shang, Na, Liu, Weidong, Li, Xian, Zhang, Lilan, Chen, Chun-Chi, Guo, Rey-Ting, Oldfield, Eric |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260892/ https://www.ncbi.nlm.nih.gov/pubmed/35811857 http://dx.doi.org/10.1021/acsomega.2c01924 |
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