Novel Mobile Phase to Control Charge States and Metal Adducts in the LC/MS for mRNA Characterization Assays

[Image: see text] Mass spectrometry is a widely used tool in the characterization of oligonucleotides. This analysis can be challenging due to the large number of possible charge states of oligonucleotides, which can limit the sensitivity of the assay, along with the propensity of oligonucleotides t...

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Detalles Bibliográficos
Autores principales: Strezsak, Steven R., Pimentel, Alyssa Jean, Hill, Ian T., Beuning, Penny J., Skizim, Nicholas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260895/
https://www.ncbi.nlm.nih.gov/pubmed/35811888
http://dx.doi.org/10.1021/acsomega.2c00185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260895/
https://www.ncbi.nlm.nih.gov/pubmed/35811888
http://dx.doi.org/10.1021/acsomega.2c00185

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