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Novel Mobile Phase to Control Charge States and Metal Adducts in the LC/MS for mRNA Characterization Assays
[Image: see text] Mass spectrometry is a widely used tool in the characterization of oligonucleotides. This analysis can be challenging due to the large number of possible charge states of oligonucleotides, which can limit the sensitivity of the assay, along with the propensity of oligonucleotides t...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260895/ https://www.ncbi.nlm.nih.gov/pubmed/35811888 http://dx.doi.org/10.1021/acsomega.2c00185 |