Design and Synthesis of Carbothioamide/Carboxamide-Based Pyrazoline Analogs as Potential Anticancer Agents: Apoptosis, Molecular Docking, ADME Assay, and DNA Binding Studies

[Image: see text] To discover anticancer drugs with novel structures and expand our research scope, pyrazoline derivatives (3a–3l) were designed and synthesized through cyclization of chalcones with thiosemicarbazide/semicarbazide in CH(3)COOH as a solvent. All newly synthesized pyrazoline derivativ...

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Detalles Bibliográficos
Autores principales: Rana, Manish, Faizan, Md Imam, Dar, Sajad Hussain, Ahmad, Tanveer, Rahisuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260921/
https://www.ncbi.nlm.nih.gov/pubmed/35811873
http://dx.doi.org/10.1021/acsomega.2c02033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260921/
https://www.ncbi.nlm.nih.gov/pubmed/35811873
http://dx.doi.org/10.1021/acsomega.2c02033

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