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Design and Synthesis of Carbothioamide/Carboxamide-Based Pyrazoline Analogs as Potential Anticancer Agents: Apoptosis, Molecular Docking, ADME Assay, and DNA Binding Studies

[Image: see text] To discover anticancer drugs with novel structures and expand our research scope, pyrazoline derivatives (3a–3l) were designed and synthesized through cyclization of chalcones with thiosemicarbazide/semicarbazide in CH(3)COOH as a solvent. All newly synthesized pyrazoline derivativ...

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Detalles Bibliográficos
Autores principales:	Rana, Manish, Faizan, Md Imam, Dar, Sajad Hussain, Ahmad, Tanveer, Rahisuddin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260921/ https://www.ncbi.nlm.nih.gov/pubmed/35811873 http://dx.doi.org/10.1021/acsomega.2c02033

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