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Preclinical anti‐angiogenic and anti‐cancer activities of BAY1143269 in glioblastoma via targeting oncogenic protein expression

Glioblastoma angiogenesis is critical for tumor growth, making it an appealing target for treatment development. BAY1143269 is a novel inhibitor of mitogen‐activated protein kinase interacting serine/threonine‐protein kinase 1 (MKN1) and has potent anti‐cancer activity. We identified BAY1143269 as a...

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Detalles Bibliográficos
Autores principales: Wan, Weifeng, Zhang, Xin, Huang, Changren, Chen, Ligang, Yang, Xiaobo, Bao, Kunyang, Peng, Tangming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260954/
https://www.ncbi.nlm.nih.gov/pubmed/35796398
http://dx.doi.org/10.1002/prp2.981