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Single-case experimental designs for bumetanide across neurodevelopmental disorders: BUDDI protocol

BACKGROUND: Bumetanide is a selective NKCC1 chloride importer antagonist which is being repurposed as a mechanism-based treatment for neurodevelopmental disorders (NDDs). Due to their specific actions, these kinds of interventions will only be effective in particular subsets of patients. To anticipa...

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Detalles Bibliográficos
Autores principales: Geertjens, Lisa, Cristian, Gianina, Haspels, Eva, Ramautar, Jennifer, van der Wilt, Gert Jan, Verhage, Matthijs, Bruining, Hilgo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9260985/
https://www.ncbi.nlm.nih.gov/pubmed/35799144
http://dx.doi.org/10.1186/s12888-022-04033-8