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Associations between polygenic risk, negative symptoms, and functional connectome topology during a working memory task in early-onset schizophrenia

Working memory (WM) deficit in schizophrenia is thought to arise from a widespread neural inefficiency. However, we do not know if this deficit results from the illness-related genetic risk and influence the symptom burden in various domains, especially in patients who have an early onset illness. W...

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Detalles Bibliográficos
Autores principales: Deng, Mengjie, Liu, Zhening, Zhang, Wen, Wu, Zhipeng, Cao, Hengyi, Yang, Jie, Palaniyappan, Lena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261080/
https://www.ncbi.nlm.nih.gov/pubmed/35853905
http://dx.doi.org/10.1038/s41537-022-00260-w