Rational identification of small molecules derived from 9,10-dihydrophenanthrene as potential inhibitors of 3CL(pro) enzyme for COVID-19 therapy: a computer-aided drug design approach

Small molecules such as 9,10-dihydrophenanthrene derivatives have remarkable activity toward inhibition of SARS-CoV-2 3CL(pro) and COVID-19 proliferation, which show a strong correlation between their structures and bioactivity. Therefore, these small compounds could be suitable for clinical pharmac...

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Detalles Bibliográficos
Autores principales: Daoui, Ossama, Elkhattabi, Souad, Chtita, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261181/
https://www.ncbi.nlm.nih.gov/pubmed/35818588
http://dx.doi.org/10.1007/s11224-022-02004-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261181/
https://www.ncbi.nlm.nih.gov/pubmed/35818588
http://dx.doi.org/10.1007/s11224-022-02004-z

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