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Opposing Roles of Wild-type and Mutant p53 in the Process of Epithelial to Mesenchymal Transition
The central role of an aberrantly activated EMT program in defining the critical features of aggressive carcinomas is well documented and includes cell plasticity, metastatic dissemination, drug resistance, and cancer stem cell-like phenotypes. The p53 tumor suppressor is critical for leashing off a...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261265/ https://www.ncbi.nlm.nih.gov/pubmed/35813818 http://dx.doi.org/10.3389/fmolb.2022.928399 |