NAMPT Inhibition Induces Neuroblastoma Cell Death and Blocks Tumor Growth

High-risk neuroblastoma (NB) portends very poor prognoses in children. Targeting tumor metabolism has emerged as a novel therapeutic strategy. High levels of nicotinamide-adenine-dinucleotide (NAD+) are required for rapid cell proliferation. Nicotinamide phosphoribosyl transferase (NAMPT) is the rat...

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Detalles Bibliográficos
Autores principales: Vallejo, Frederic A., Sanchez, Anthony, Cuglievan, Branko, Walters, Winston M., De Angulo, Guillermo, Vanni, Steven, Graham, Regina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261286/
https://www.ncbi.nlm.nih.gov/pubmed/35814452
http://dx.doi.org/10.3389/fonc.2022.883318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261286/
https://www.ncbi.nlm.nih.gov/pubmed/35814452
http://dx.doi.org/10.3389/fonc.2022.883318

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