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Obesity Accelerates Age-Associated Defects in Human B Cells Through a Metabolic Reprogramming Induced by the Fatty Acid Palmitate
We have measured the secretion of autoimmune antibodies in plasma samples and in culture supernatants of blood-derived B cells from four groups of individuals: young lean (Y(L)), elderly lean (E(L)), young obese (Y(O)) and elderly obese (E(O)). We found secretion comparable in Y(O) and E(L) individu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261304/ https://www.ncbi.nlm.nih.gov/pubmed/35822047 http://dx.doi.org/10.3389/fragi.2021.828697 |