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mTORC1 Crosstalk With Stress Granules in Aging and Age-Related Diseases

The mechanistic target of rapamycin complex 1 (mTORC1) kinase is a master regulator of metabolism and aging. A complex signaling network converges on mTORC1 and integrates growth factor, nutrient and stress signals. Aging is a dynamic process characterized by declining cellular survival, renewal, an...

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Detalles Bibliográficos
Autores principales: Cadena Sandoval, Marti, Heberle, Alexander Martin, Rehbein, Ulrike, Barile, Cecilia, Ramos Pittol, José Miguel, Thedieck, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9261333/
https://www.ncbi.nlm.nih.gov/pubmed/35822040
http://dx.doi.org/10.3389/fragi.2021.761333